Multidrug-resistant patients receiving treatment in Niger who are infected with M. tuberculosis Cameroon family convert faster in smear and culture than those with M …
M Ejo, S Hassane-Harouna, MB Souleymane… - Tuberculosis, 2020 - Elsevier
In this study, we analyzed the M. tuberculosis complex (MTBc) population structure among
multidrug-resistant TB (MDR-TB) patients in Niger and tested whether the Cameroon family
displayed a slower response to MDR-TB treatment. We genotyped baseline clinical isolates
that had been collected from pulmonary MDR-TB patients recruited consecutively between
2008 and 2016 in Niger. Spoligotyping was used to analyze the genetic diversity of
mycobacterial lineages, and Kaplan Meier's analysis to compare treatment outcomes. A total …
multidrug-resistant TB (MDR-TB) patients in Niger and tested whether the Cameroon family
displayed a slower response to MDR-TB treatment. We genotyped baseline clinical isolates
that had been collected from pulmonary MDR-TB patients recruited consecutively between
2008 and 2016 in Niger. Spoligotyping was used to analyze the genetic diversity of
mycobacterial lineages, and Kaplan Meier's analysis to compare treatment outcomes. A total …
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